It is a benign condition with a difference in pupil size of less than or equal to 1 mm. Physiologic (also known as simple or essential) anisocoria is the most common cause of unequal pupil sizes, affecting up to 20% of the population. An injury or lesion in either pathway may result in changes in pupil size. Generally, anisocoria is caused by impaired dilation (a sympathetic response) or impaired constriction (a parasympathetic response) of pupils. Thus, thorough clinical evaluation is important for appropriate diagnosis and management of the underlying cause. It is relatively common, and causes vary from benign physiologic anisocoria to potentially life-threatening emergencies. © 2019 Neuro-ophthalmology Virtual Education Library: NOVEL Īnisocoria indicates unequal pupil sizes. Sympathetic and parasympathetic innervation of pupillary dilation during sustained processing. Clinical methods: The history, physical, and laboratory examinations. Pupil size variation as an indication of affective processing. diseases-conditions/horner-syndrome/symptoms-causes/syc-20373547 health-library/diseases-and-conditions/i/iritis.html Does a normal‐shaped pupil exclude the diagnosis of iritis. Relationship between sedation and pupillary function: comparison of diazepam and diphenhydramine. Human eyes with dilated pupils induce pupillary contagion in infants. (2014) Why are my pupils so naturally large? aao.org/eye-health/ask-ophthalmologist-q/why-are-my-pupils-large What is anisocoria? aao.org/eye-health/diseases/what-is-anisocoria theeyeshaveit/medica/anticholinergics.html You can learn more about how we ensure our content is accurate and current by reading our editorial policy. Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. But overall, most adults should have their vision checked every couple of years. How often you get your vision checked depends on your age and certain health factors. Visit your doctor if you notice changes in your pupil size that are unrelated to light and viewing distance or if you’re having any changes or problems with your vision.
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